Abstract: The effects of relative process parameters on the microstructure and microhardness of Ni60 alloy powder during laser cladding were studied by orthogonal test method.The microhardness and microstructure of different parameters were analyzed.The results show that the microhardness of the cladding layer under different process parameters is basically the same, mainly concentrates in 680-720 HV, and the height of the cladding layer fluctuates greatly.The crystal structure size of the cladding layer decreases first and then increases with the increase of the degree of subcooling.As the dilution rate decreases, the crystal size decreases gradually.The microstructure of the cladding layer is roughly dendritic, isometric, back or the relationship between a planar or cellular crystal and a columnar crystal transition or several of these transitions.